Detalhe da pesquisa
1.
Biomarkers of aging for the identification and evaluation of longevity interventions.
Cell;
186(18): 3758-3775, 2023 08 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37657418
2.
Interrogating Precision Electrophile Signaling.
Trends Biochem Sci;
44(4): 380-381, 2019 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30765181
3.
We need to shift the focus of aging research to aging itself.
Proc Natl Acad Sci U S A;
120(37): e2307449120, 2023 09 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37682890
4.
Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1.
FASEB J;
33(12): 14636-14652, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31665914
5.
Redox Signaling by Reactive Electrophiles and Oxidants.
Chem Rev;
118(18): 8798-8888, 2018 09 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30148624
6.
Getting the Message? Native Reactive Electrophiles Pass Two Out of Three Thresholds to be Bona Fide Signaling Mediators.
Bioessays;
40(5): e1700240, 2018 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29603288
7.
On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry.
J Am Chem Soc;
138(11): 3610-22, 2016 Mar 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26907082
8.
Correction to Redox Signaling by Reactive Electrophiles and Oxidants.
Chem Rev;
119(6): 4464-4469, 2019 Mar 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30789714
9.
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Nat Aging;
4(2): 261-274, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38200273
10.
Validation of biomarkers of aging.
Nat Med;
30(2): 360-372, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38355974
11.
Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites.
J Vis Exp;
(196)2023 06 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37335096
12.
Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish.
Nat Protoc;
18(5): 1379-1415, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37020146
13.
Biological age is increased by stress and restored upon recovery.
Cell Metab;
35(5): 807-820.e5, 2023 05 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37086720
14.
Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna.
Sci Adv;
8(37): eabo5482, 2022 09 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36112674
15.
Z-REX uncovers a bifurcation in function of Keap1 paralogs.
Elife;
112022 10 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36300632
16.
Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera.
Nat Commun;
12(1): 5736, 2021 09 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34593792
17.
Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals.
Front Aging Neurosci;
12: 1, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32116644
18.
The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor.
Helv Chim Acta;
103(5)2020 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34113045
19.
Weighing up the Selenocysteome Uncovers New Sec-rets.
Cell Chem Biol;
25(11): 1315-1317, 2018 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30445052
20.
Author Correction: Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish.
Nat Protoc;
18(10): 3155, 2023 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37340167